Nimesulide

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) widely used for its effective anti-inflammatory, analgesic, and antipyretic properties. It is commonly prescribed for the treatment of acute pain, primary dysmenorrhea, and inflammation associated with musculoskeletal conditions.

Key Features

• Chemical Formula: C13H12N2O5S
• Molecular Weight: 308.31 g/mol
• Form: Available in various forms such as tablets, powders, or suspensions for medical and industrial applications.
• Mechanism of Action: Inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the synthesis of prostaglandins that cause pain and inflammation.

Applications

1. Pharmaceutical Use:

   • Treatment of acute pain (e.g., postoperative or dental pain).
   • Management of inflammation in osteoarthritis, rheumatoid arthritis, and other joint disorders.
   • Relief from primary dysmenorrhea and other menstrual pains.

2. Research and Development:

   • Utilized in the formulation of new NSAID-based drugs.
   • Studied for its selective COX-2 inhibition mechanism.